SAPONIN NANOPARTICLE ADJUVANTS INCORPORATING TOLL-LIKE RECEPTOR AGONISTS IMPROVE VACCINE IMMUNOMODULATION Ou, B.S.^; Baillet, J.^; Filsinger Interrante, M.V.; Adamska, J.S.; Zhou, X.; Saouaf, O.A.; Yan, J.; Klich, J.H.; Jons, C.K.; Meany, E.L.;

SAPONIN NANOPARTICLE ADJUVANTS INCORPORATING TOLL-LIKE RECEPTOR AGONISTS IMPROVE VACCINE IMMUNOMODULATION

Ou, B.S.^; Baillet, J.^; Filsinger Interrante, M.V.; Adamska, J.S.; Zhou, X.; Saouaf, O.A.; Yan, J.; Klich, J.H.; Jons, C.K.; Meany, E.L.; Valdez, A.; Carter, L.; Pulendran, B.; King, N.P.; Appel, E.A.* Science Advances (2024) PDF

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WATER-ENHANCING GELS EXHIBITING HEAT-ACTIVATED FORMATION OF SILICA AEROGELS FOR PROTECTION OF CRITICAL INFRASTRUCTURE DURING CATASTROPHIC WILDFIRE Dong, C.; d'Aquino, A.I.; Sen, S.; Hall, I.A.; Yu, A.C.; Acosta, J.D.; Appel, E.A.* Advanced Mat

WATER-ENHANCING GELS EXHIBITING HEAT-ACTIVATED FORMATION OF SILICA AEROGELS FOR PROTECTION OF CRITICAL INFRASTRUCTURE DURING CATASTROPHIC WILDFIRE

Dong, C.; d'Aquino, A.I.; Sen, S.; Hall, I.A.; Yu, A.C.; Acosta, J.D.; Appel, E.A.* Advanced Materials (2024) PDF

Check out some cool burn videos of our hydrogel technology compared to commercial products!

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NANOPARTICLE-CONJUGATED TLR9 AGONISTS IMPROVE THE POTENCY, DURABILITY, AND BREADTH OF COVID-19 VACCINES Ou, B.S.^; Baillet, J.^; Picece, V.C.T.M.^; Gale, E.C.; Powell, A.E.; Saouaf, O.M.; Yan, J.; Nejatfard, A.; Lopez Hernandez, H.; Appel, E.A.

NANOPARTICLE-CONJUGATED TLR9 AGONISTS IMPROVE THE POTENCY, DURABILITY, AND BREADTH OF COVID-19 VACCINES

Ou, B.S.^; Baillet, J.^; Picece, V.C.T.M.^; Gale, E.C.; Powell, A.E.; Saouaf, O.M.; Yan, J.; Nejatfard, A.; Lopez Hernandez, H.; Appel, E.A.* ACS Nano (2024) PDF

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BIOMATERIALS TO ENHANCE ADOPTIVE CELL THERAPY Eckman, N.^; Nejatfard, A.^; Cavet, R.; Grosskopf, A.K.*; Appel, E.A.* Nature Reviews Bioengineering (2024) PDF

BIOMATERIALS TO ENHANCE ADOPTIVE CELL THERAPY

Eckman, N.^; Nejatfard, A.^; Cavet, R.; Grosskopf, A.K.*; Appel, E.A.* Nature Reviews Bioengineering (2024) PDF

A cGAMP-CONTAINING HYDROGEL FOR PROLONGED SARS-COV-2 RBD SUBUNIT VACCINE EXPOSURE INDUCES A BROAD AND POTENT HUMORAL RESPONSE Bohnert, V.^; Gale, E.C.^; Lahey, L.J.^; Yan, J.; Powell, A.E.; Ou, B.S.; Carozza, J.A.; Li, L.*; Appel, E.A.* Advanc

A cGAMP-CONTAINING HYDROGEL FOR PROLONGED SARS-COV-2 RBD SUBUNIT VACCINE EXPOSURE INDUCES A BROAD AND POTENT HUMORAL RESPONSE

Bohnert, V.^; Gale, E.C.^; Lahey, L.J.^; Yan, J.; Powell, A.E.; Ou, B.S.; Carozza, J.A.; Li, L.*; Appel, E.A.* Advanced NanoBiomed Research (2024) PDF

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DEFINING STRUCTURE-FUNCTION RELATIONSHIPS OF AMPHIPHILIC EXCIPIENTS ENABLES RATIONAL DESIGN OF ULTRA-STABLE BIOPHARMACEUTICALS Prossnitz, A.N.; Nguyen, L.T.; Eckman, N.; Borker, S.; Tetef, S.; Autzen, A.A.A.; Fuller, G.G.; Appel, E.A.* Advance

DEFINING STRUCTURE-FUNCTION RELATIONSHIPS OF AMPHIPHILIC EXCIPIENTS ENABLES RATIONAL DESIGN OF ULTRA-STABLE BIOPHARMACEUTICALS

Prossnitz, A.N.; Nguyen, L.T.; Eckman, N.; Borker, S.; Tetef, S.; Autzen, A.A.A.; Fuller, G.G.; Appel, E.A.* Advanced Science (2024) PDF

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BIOMIMETIC NON-ERGODIC AGING BY DYNAMIC-TO-COVALENT TRANSITIONS IN PHYSICAL HYDROGELS Sen, S.; Dong, C.; d’Aquino, A.I.; Yu, A.C.; Appel, E.A.* ACS Applied Materials & Interfaces (2024) PDF Check out the Arxiv preprint of this

BIOMIMETIC NON-ERGODIC AGING BY DYNAMIC-TO-COVALENT TRANSITIONS IN PHYSICAL HYDROGELS

Sen, S.; Dong, C.; d’Aquino, A.I.; Yu, A.C.; Appel, E.A.* ACS Applied Materials & Interfaces (2024) PDF

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ELECTROCHEMICALLY MUTABLE SOFT METASURFACES Doshi, S.; Ji, A.; Mahdi, A.I.; Keene, S.T.; Selvin, S.; Lalanne, P.; Appel, E.A.; Melosh, N.A.*; Brongersma, M.L.* Nature Materials (2024) PDF

ELECTROCHEMICALLY MUTABLE SOFT METASURFACES

Doshi, S.; Ji, A.; Mahdi, A.I.; Keene, S.T.; Selvin, S.; Lalanne, P.; Appel, E.A.; Melosh, N.A.*; Brongersma, M.L.* Nature Materials (2024) PDF

DYNAMIC HYDROGEL CROSSLINK STRENGTH CONTROLS YIELDING CHARACTERISTICS AND CELL VIABILITY DURING INJECTION Eckman, N.; Grosskopf, A.K.; Jiang, G.; Kamani, K.; Huang, M.S.; Schmittlein, B.; Heilshorn, S.C.; Rogers, S.; Appel, E.A.* Biomaterials

DYNAMIC HYDROGEL CROSSLINK STRENGTH CONTROLS YIELDING CHARACTERISTICS AND CELL VIABILITY DURING INJECTION

Eckman, N.; Grosskopf, A.K.; Jiang, G.; Kamani, K.; Huang, M.S.; Schmittlein, B.; Heilshorn, S.C.; Rogers, S.; Appel, E.A.* Biomaterials Science (2024) PDF

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VIRAL VECTOR ELUTING LENSES FOR SINGLE-STEP TARGETED EXPRESSION OF GENETICALLY-ENCODED ACTIVITY SENSORS FOR IN VIVO MICROENDOSCOPIC CALCIUM IMAGING Jons, C; Cheng, D.; Dong, C.; Meany, E.; Nassi, J.*; Appel, E.A.* Macromolecular Biosciences (

VIRAL VECTOR ELUTING LENSES FOR SINGLE-STEP TARGETED EXPRESSION OF GENETICALLY-ENCODED ACTIVITY SENSORS FOR IN VIVO MICROENDOSCOPIC CALCIUM IMAGING

Jons, C; Cheng, D.; Dong, C.; Meany, E.; Nassi, J.*; Appel, E.A.* Macromolecular Biosciences (2024) PDF

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LABEL-FREE COMPOSITION ANALYSIS OF SUPRAMOLECULAR POLYMER-NANOPARTICLE HYDROGELS BY REVERSED-PHASE LIQUID CHROMATOGRAPHY COUPLED WITH A CHARGED AEROSOL DETECTOR Tang, S.^; Pederson, Z.^; Meany, E.L.; Yen, C.-W.; Swansiger, A.K.; Prell, J.S

LABEL-FREE COMPOSITION ANALYSIS OF SUPRAMOLECULAR POLYMER-NANOPARTICLE HYDROGELS BY REVERSED-PHASE LIQUID CHROMATOGRAPHY COUPLED WITH A CHARGED AEROSOL DETECTOR

Tang, S.^; Pederson, Z.^; Meany, E.L.; Yen, C.-W.; Swansiger, A.K.; Prell, J.S.; Chen, B.; Grosskopf, A.K.; Eckman, N.; Jiang, G.; Baillet, J.; Pellett, J.D.; Appel, E.A.* Analytical Chem (2024) PDF

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COMPOSITE GELS DESIGNED TO STICK TO BIOLOGICAL TISSUES Bailey, S.J.; Appel, E.A.* Nature (2024) PDF Check out the original article in Nature Chem Eng by Prof. Bozhi Tian and coworkers.

COMPOSITE GELS DESIGNED TO STICK TO BIOLOGICAL TISSUES

Bailey, S.J.; Appel, E.A.* Nature (2024) PDF

Check out the original article in Nature Chem Eng by Prof. Bozhi Tian and coworkers.

CLONALLY EXPANDED TARGETABLE NATURAL KILLER-LIKE NKG7 T CELLS SEED THE AGED SPINAL CORD TO DISRUPT MYELOID-DEPENDENT WOUND HEALING Kong, G.; Zhou, L.; Song, Y.; Yan, Y.; Calderazzo, S.M.; Saddala, M.S.; De Labastida Rivera, F.; Cherry, J.; Eckman

CLONALLY EXPANDED TARGETABLE NATURAL KILLER-LIKE NKG7 T CELLS SEED THE AGED SPINAL CORD TO DISRUPT MYELOID-DEPENDENT WOUND HEALING

Kong, G.; Zhou, L.; Song, Y.; Yan, Y.; Calderazzo, S.M.; Saddala, M.S.; De Labastida Rivera, F.; Cherry, J.; Eckman, N.; Appel, E.A.; Velenosi, A.; Swarup, V.; Kawaguchi, R.; Ng, S.S.; Kwon, B.; Gate, D.; Geschwind, D.; Engwerda, C.; Di Giovanni, S.* Neuron (2024) PDF

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SAPONIN NANOPARTICLE ADJUVANTS INCORPORATING TOLL-LIKE RECEPTOR AGONISTS IMPROVE VACCINE IMMUNOMODULATION Ou, B.S.^; Baillet, J.^; Filsinger Interrante, M.V.; Adamska, J.S.; Zhou, X.; Saouaf, O.A.; Yan, J.; Klich, J.H.; Jons, C.K.; Meany, E.L.;
WATER-ENHANCING GELS EXHIBITING HEAT-ACTIVATED FORMATION OF SILICA AEROGELS FOR PROTECTION OF CRITICAL INFRASTRUCTURE DURING CATASTROPHIC WILDFIRE Dong, C.; d'Aquino, A.I.; Sen, S.; Hall, I.A.; Yu, A.C.; Acosta, J.D.; Appel, E.A.* Advanced Mat
NANOPARTICLE-CONJUGATED TLR9 AGONISTS IMPROVE THE POTENCY, DURABILITY, AND BREADTH OF COVID-19 VACCINES Ou, B.S.^; Baillet, J.^; Picece, V.C.T.M.^; Gale, E.C.; Powell, A.E.; Saouaf, O.M.; Yan, J.; Nejatfard, A.; Lopez Hernandez, H.; Appel, E.A.
BIOMATERIALS TO ENHANCE ADOPTIVE CELL THERAPY Eckman, N.^; Nejatfard, A.^; Cavet, R.; Grosskopf, A.K.*; Appel, E.A.* Nature Reviews Bioengineering (2024) PDF
A cGAMP-CONTAINING HYDROGEL FOR PROLONGED SARS-COV-2 RBD SUBUNIT VACCINE EXPOSURE INDUCES A BROAD AND POTENT HUMORAL RESPONSE Bohnert, V.^; Gale, E.C.^; Lahey, L.J.^; Yan, J.; Powell, A.E.; Ou, B.S.; Carozza, J.A.; Li, L.*; Appel, E.A.* Advanc
DEFINING STRUCTURE-FUNCTION RELATIONSHIPS OF AMPHIPHILIC EXCIPIENTS ENABLES RATIONAL DESIGN OF ULTRA-STABLE BIOPHARMACEUTICALS Prossnitz, A.N.; Nguyen, L.T.; Eckman, N.; Borker, S.; Tetef, S.; Autzen, A.A.A.; Fuller, G.G.; Appel, E.A.* Advance
BIOMIMETIC NON-ERGODIC AGING BY DYNAMIC-TO-COVALENT TRANSITIONS IN PHYSICAL HYDROGELS Sen, S.; Dong, C.; d’Aquino, A.I.; Yu, A.C.; Appel, E.A.* ACS Applied Materials & Interfaces (2024) PDF Check out the Arxiv preprint of this
ELECTROCHEMICALLY MUTABLE SOFT METASURFACES Doshi, S.; Ji, A.; Mahdi, A.I.; Keene, S.T.; Selvin, S.; Lalanne, P.; Appel, E.A.; Melosh, N.A.*; Brongersma, M.L.* Nature Materials (2024) PDF
DYNAMIC HYDROGEL CROSSLINK STRENGTH CONTROLS YIELDING CHARACTERISTICS AND CELL VIABILITY DURING INJECTION Eckman, N.; Grosskopf, A.K.; Jiang, G.; Kamani, K.; Huang, M.S.; Schmittlein, B.; Heilshorn, S.C.; Rogers, S.; Appel, E.A.* Biomaterials
VIRAL VECTOR ELUTING LENSES FOR SINGLE-STEP TARGETED EXPRESSION OF GENETICALLY-ENCODED ACTIVITY SENSORS FOR IN VIVO MICROENDOSCOPIC CALCIUM IMAGING Jons, C; Cheng, D.; Dong, C.; Meany, E.; Nassi, J.*; Appel, E.A.* Macromolecular Biosciences (
LABEL-FREE COMPOSITION ANALYSIS OF SUPRAMOLECULAR POLYMER-NANOPARTICLE HYDROGELS BY REVERSED-PHASE LIQUID CHROMATOGRAPHY COUPLED WITH A CHARGED AEROSOL DETECTOR Tang, S.^; Pederson, Z.^; Meany, E.L.; Yen, C.-W.; Swansiger, A.K.; Prell, J.S
COMPOSITE GELS DESIGNED TO STICK TO BIOLOGICAL TISSUES Bailey, S.J.; Appel, E.A.* Nature (2024) PDF Check out the original article in Nature Chem Eng by Prof. Bozhi Tian and coworkers.
CLONALLY EXPANDED TARGETABLE NATURAL KILLER-LIKE NKG7 T CELLS SEED THE AGED SPINAL CORD TO DISRUPT MYELOID-DEPENDENT WOUND HEALING Kong, G.; Zhou, L.; Song, Y.; Yan, Y.; Calderazzo, S.M.; Saddala, M.S.; De Labastida Rivera, F.; Cherry, J.; Eckman