DELIVERY OF CAR-T CELLS IN A TRANSIENT INJECTABLE STIMULATORY NICHE IMPROVES TREATMENT OF SOLID TUMORS Grosskopf, A.K.^; Labanieh, L.^; Klysz, D.D.; Roth, G.A.; Xu, P.; Adebowale, O.; Gale, E.C.; Jons, C.K.; Klich, J.H.; Yan, J.; Maikawa, C.L.;

DELIVERY OF CAR-T CELLS IN A TRANSIENT INJECTABLE STIMULATORY NICHE IMPROVES TREATMENT OF SOLID TUMORS

Grosskopf, A.K.^; Labanieh, L.^; Klysz, D.D.; Roth, G.A.; Xu, P.; Adebowale, O.; Gale, E.C.; Jons, C.K.; Klich, J.H.; Yan, J.; Maikawa, C.L.; Correa, S.; Ou, B.S.; d’Aquino, A.I.; Cochran, J.R.; Chaudhuri, O.; Mackall, C.L.*; Appel, E.A.* Science Advances (2022) PDF

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Check out the BioRxiv preprint of this work

DESIGNING SPATIAL AND TEMPORAL CONTROL OF VACCINE RESPONSES Roth, G.A.; Picece, V.T.M.; Ou, B.S.; Luo, W.; Pulendran, B.; Appel, E.A.* Nature Reviews Materials (2022) PDF

DESIGNING SPATIAL AND TEMPORAL CONTROL OF VACCINE RESPONSES

Roth, G.A.; Picece, V.T.M.; Ou, B.S.; Luo, W.; Pulendran, B.; Appel, E.A.* Nature Reviews Materials (2022) PDF

INJECTABLE LIPOSOME BASED SUPRAMOLECULAR HYDROGELS FOR THE PROGRAMMABLE RELEASE OF MULTIPLE PROTEIN DRUGS Correa, S.^; Grosskopf, A.K.^; Klich, J.H.; Lopez Hernandez, H.; Appel, E.A.* Matter - Cell Press (2022) PDF Check out the Bio

INJECTABLE LIPOSOME BASED SUPRAMOLECULAR HYDROGELS FOR THE PROGRAMMABLE RELEASE OF MULTIPLE PROTEIN DRUGS

Correa, S.^; Grosskopf, A.K.^; Klich, J.H.; Lopez Hernandez, H.; Appel, E.A.* Matter - Cell Press (2022) PDF

Check out the BioRxiv preprint of this work

COMBINATORIAL POLYACRYLAMIDE HYDROGELS FOR PREVENTING BIOFOULING ON IMPLANTABLE BIOSENSORS Chan, D.^; Chien, J.-C.^; Axpe, E.; Blankemeier, L.; Baker, S.W.; Swaminathan, S.; Piunova, V.A.; Zubarev, D.Y.; Maikawa, C.L.; Grosskopf, A.K.; Mann, J.

COMBINATORIAL POLYACRYLAMIDE HYDROGELS FOR PREVENTING BIOFOULING ON IMPLANTABLE BIOSENSORS

Chan, D.^; Chien, J.-C.^; Axpe, E.; Blankemeier, L.; Baker, S.W.; Swaminathan, S.; Piunova, V.A.; Zubarev, D.Y.; Maikawa, C.L.; Grosskopf, A.K.; Mann, J.L.; Soh, H.T.*; Appel, E.A.* Advanced Materials (2022) PDF

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YIELD-STRESS AND CREEP CONTROL DEPOT FORMATION AND PERSISTENCE OF INJECTABLE HYDROGELS FOLLOWING SUBCUTANEOUS ADMINISTRATION Jons, C.K.; Grosskopf, A.K.; Baillet, J.; Yan, J.; Klich, J.H.; Appel, E.A.* Advanced Functional Materials (2022) P

YIELD-STRESS AND CREEP CONTROL DEPOT FORMATION AND PERSISTENCE OF INJECTABLE HYDROGELS FOLLOWING SUBCUTANEOUS ADMINISTRATION

Jons, C.K.; Grosskopf, A.K.; Baillet, J.; Yan, J.; Klich, J.H.; Appel, E.A.* Advanced Functional Materials (2022) PDF

Check out the BioRxiv preprint of this work

INJECTABLE NANOPARTICLE-BASED HYDROGELS ENABLE THE SAFE AND EFFECTIVE DEPLOYMENT OF IMMUNOSTIMULATORY CD40 AGONIST ANTIBODIES Correa, S.; Meany, E.L.; Gale, E.C.; Klich, J.H.; Saouaf, O.M.; Mayer, A.T.; Xian, Z.; Liong, C.; Brown, R.A.; Maikawa

INJECTABLE NANOPARTICLE-BASED HYDROGELS ENABLE THE SAFE AND EFFECTIVE DEPLOYMENT OF IMMUNOSTIMULATORY CD40 AGONIST ANTIBODIES

Correa, S.; Meany, E.L.; Gale, E.C.; Klich, J.H.; Saouaf, O.M.; Mayer, A.T.; Xian, Z.; Liong, C.; Brown, R.A.; Maikawa, C.L.; Grosskopf, A.K.; Mann, J.L.; Idoyaga, J.; Appel, E.A.* Advanced Science (2022) PDF

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REAL-TIME MONITORING OF DRUG PHARMACOKINETICS WITHIN TUMOR TISSUE IN LIVE ANIMALS Seo, J.-W.^; Fu, K.^; Correa, S.; Eisenstein, M.; Appel, E.A.* ; Soh, H.T.* Science Advances (2022) PDF Check out the bioRxiv preprint of this w

REAL-TIME MONITORING OF DRUG PHARMACOKINETICS WITHIN TUMOR TISSUE IN LIVE ANIMALS

Seo, J.-W.^; Fu, K.^; Correa, S.; Eisenstein, M.; Appel, E.A.*; Soh, H.T.* Science Advances (2022) PDF

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EXTREME EXTENSIBILITY IN PHYSICALLY CROSSLINKED NANOCOMPOSITE HYDROGELS LEVERAGING DYNAMIC POLYMER-NANOPARTICLE INTERACTIONS Grosskopf, A.K.; Mann, J.L; Baillet, J.; Lopez Hernandez, H.; Autzen, A.A.A.; Yu, A.C.; Appel, E.A.* Macromolecules (

EXTREME EXTENSIBILITY IN PHYSICALLY CROSSLINKED NANOCOMPOSITE HYDROGELS LEVERAGING DYNAMIC POLYMER-NANOPARTICLE INTERACTIONS

Grosskopf, A.K.; Mann, J.L; Baillet, J.; Lopez Hernandez, H.; Autzen, A.A.A.; Yu, A.C.; Appel, E.A.* Macromolecules (2022) PDF

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SUSTAINED DELIVERY APPROACHES TO IMPROVING ADAPTIVE IMMUNE RESPONSES Ou, B.S.^; Saouaf, O.M.^; Baillet, J.; Appel, E.A.* Advanced Drug Delivery Reviews (2022) PDF

SUSTAINED DELIVERY APPROACHES TO IMPROVING ADAPTIVE IMMUNE RESPONSES

Ou, B.S.^; Saouaf, O.M.^; Baillet, J.; Appel, E.A.* Advanced Drug Delivery Reviews (2022) PDF

INJECTABLE POLYMER-NANOPARTICLE HYDROGEL FOR THE SUSTAINED INTRAVITREAL DELIVERY OF BIMATOPROST Meany, E.L.^; Andaya, R.^; Tang, S.; Kasse, C.M.; Fuji, R.N.; Grosskopf, A.K.; d’Aquino, A.I.; Bartoe, J.T.; Ybarra, R.; Shelton, A.; Pederson, Z.;

INJECTABLE POLYMER-NANOPARTICLE HYDROGEL FOR THE SUSTAINED INTRAVITREAL DELIVERY OF BIMATOPROST

Meany, E.L.^; Andaya, R.^; Tang, S.; Kasse, C.M.; Fuji, R.N.; Grosskopf, A.K.; d’Aquino, A.I.; Bartoe, J.T.; Ybarra, R.; Shelton, A.; Pederson, Z.; Hu, C.; Leung, D.; Nagapudi, K.; Ubhayakar, S.; Yen, C.W.*; Appel, E.A.* Advanced Therapeutics (2022) PDF

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STABLE HIGH-CONCENTRATION MONOCLONAL ANTIBODY FORMULATIONS ENABLED BY AN AMPHIPHILIC COPOLYMER EXCIPIENT Klich, J.H.^; Kasse, C.M.^; Mann, J.L.; Huang, Y.; d’Aquino, A.I.; Grosskopf, A.K.; Baillet, J.; Fuller, G.G.; Appel, E.A.* Advanced Thera

STABLE HIGH-CONCENTRATION MONOCLONAL ANTIBODY FORMULATIONS ENABLED BY AN AMPHIPHILIC COPOLYMER EXCIPIENT

Klich, J.H.^; Kasse, C.M.^; Mann, J.L.; Huang, Y.; d’Aquino, A.I.; Grosskopf, A.K.; Baillet, J.; Fuller, G.G.; Appel, E.A.* Advanced Therapeutics (2022) PDF

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FORMULATION EXCIPIENTS AND THEIR ROLE IN INSULIN STABILITY AND ASSOCIATION STATE IN FORMULATION Maikawa, C.L.; Nguyen, L.T.; Mann, J.L.; Appel, E.A.* Pharmaceutical Research (2022) PDF

FORMULATION EXCIPIENTS AND THEIR ROLE IN INSULIN STABILITY AND ASSOCIATION STATE IN FORMULATION

Maikawa, C.L.; Nguyen, L.T.; Mann, J.L.; Appel, E.A.* Pharmaceutical Research (2022) PDF

MULTIMERIZATION OF EBOLA GPMUCIN ON PROTEIN NANOPARTICLE VACCINES HAS MINIMAL EFFECT ON ELICITATION OF NEUTRALIZING ANTIBODIES Powell, A.E.; Xu, D.; Roth, G.A.; Zhang, K.; Chiu, W.; Appel, E.A.; Kim, P.S.* Frontiers in Immunology (2022) PDF

MULTIMERIZATION OF EBOLA GPMUCIN ON PROTEIN NANOPARTICLE VACCINES HAS MINIMAL EFFECT ON ELICITATION OF NEUTRALIZING ANTIBODIES

Powell, A.E.; Xu, D.; Roth, G.A.; Zhang, K.; Chiu, W.; Appel, E.A.; Kim, P.S.* Frontiers in Immunology (2022) PDF

PNP HYDROGEL PREVENTS SYMBLEPHARA FORMATION IN MICE AFTER OCULAR ALKALI INJURY Swarup, A.; Grosskopf, A.K.; Stapleton, L.M.; Subramanium, V.R.; Li, B.; Weissman, I.L.; Appel, E.A.; Wu, A.Y.* Translational Vision Science & Technology (2022

PNP HYDROGEL PREVENTS SYMBLEPHARA FORMATION IN MICE AFTER OCULAR ALKALI INJURY

Swarup, A.; Grosskopf, A.K.; Stapleton, L.M.; Subramanium, V.R.; Li, B.; Weissman, I.L.; Appel, E.A.; Wu, A.Y.* Translational Vision Science & Technology (2022) PDF

THE LIVING INTERFACE BETWEEN SYNTHETIC BIOLOGY AND BIOMATERIAL DESIGN Liu, A.P.*; Appel, E.A.; Ashby, P.D.; Baker, B.M.; Franco, E.; Gu, L.; Haynes, K.; Joshi, N.S.; Kloxin, A.M.; Kouwer, P.H.J.; Mittal, J.; Morsut, L.; Noireaux, V.; Parekh, S.

THE LIVING INTERFACE BETWEEN SYNTHETIC BIOLOGY AND BIOMATERIAL DESIGN

Liu, A.P.*; Appel, E.A.; Ashby, P.D.; Baker, B.M.; Franco, E.; Gu, L.; Haynes, K.; Joshi, N.S.; Kloxin, A.M.; Kouwer, P.H.J.; Mittal, J.; Morsut, L.; Noireaux, V.; Parekh, S.; Schulman, R.; Tang, S.K.Y.; Valentine, M.T.; Vega, S.L.; Weber, W.; Stephanopoulos, N.; Chaudhuri, O.* Nature Materials (2022) PDF

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DELIVERY OF CAR-T CELLS IN A TRANSIENT INJECTABLE STIMULATORY NICHE IMPROVES TREATMENT OF SOLID TUMORS Grosskopf, A.K.^; Labanieh, L.^; Klysz, D.D.; Roth, G.A.; Xu, P.; Adebowale, O.; Gale, E.C.; Jons, C.K.; Klich, J.H.; Yan, J.; Maikawa, C.L.;
DESIGNING SPATIAL AND TEMPORAL CONTROL OF VACCINE RESPONSES Roth, G.A.; Picece, V.T.M.; Ou, B.S.; Luo, W.; Pulendran, B.; Appel, E.A.* Nature Reviews Materials (2022) PDF
INJECTABLE LIPOSOME BASED SUPRAMOLECULAR HYDROGELS FOR THE PROGRAMMABLE RELEASE OF MULTIPLE PROTEIN DRUGS Correa, S.^; Grosskopf, A.K.^; Klich, J.H.; Lopez Hernandez, H.; Appel, E.A.* Matter - Cell Press (2022) PDF Check out the Bio
COMBINATORIAL POLYACRYLAMIDE HYDROGELS FOR PREVENTING BIOFOULING ON IMPLANTABLE BIOSENSORS Chan, D.^; Chien, J.-C.^; Axpe, E.; Blankemeier, L.; Baker, S.W.; Swaminathan, S.; Piunova, V.A.; Zubarev, D.Y.; Maikawa, C.L.; Grosskopf, A.K.; Mann, J.
YIELD-STRESS AND CREEP CONTROL DEPOT FORMATION AND PERSISTENCE OF INJECTABLE HYDROGELS FOLLOWING SUBCUTANEOUS ADMINISTRATION Jons, C.K.; Grosskopf, A.K.; Baillet, J.; Yan, J.; Klich, J.H.; Appel, E.A.* Advanced Functional Materials (2022) P
INJECTABLE NANOPARTICLE-BASED HYDROGELS ENABLE THE SAFE AND EFFECTIVE DEPLOYMENT OF IMMUNOSTIMULATORY CD40 AGONIST ANTIBODIES Correa, S.; Meany, E.L.; Gale, E.C.; Klich, J.H.; Saouaf, O.M.; Mayer, A.T.; Xian, Z.; Liong, C.; Brown, R.A.; Maikawa
REAL-TIME MONITORING OF DRUG PHARMACOKINETICS WITHIN TUMOR TISSUE IN LIVE ANIMALS Seo, J.-W.^; Fu, K.^; Correa, S.; Eisenstein, M.; Appel, E.A.* ; Soh, H.T.* Science Advances (2022) PDF Check out the bioRxiv preprint of this w
EXTREME EXTENSIBILITY IN PHYSICALLY CROSSLINKED NANOCOMPOSITE HYDROGELS LEVERAGING DYNAMIC POLYMER-NANOPARTICLE INTERACTIONS Grosskopf, A.K.; Mann, J.L; Baillet, J.; Lopez Hernandez, H.; Autzen, A.A.A.; Yu, A.C.; Appel, E.A.* Macromolecules (
SUSTAINED DELIVERY APPROACHES TO IMPROVING ADAPTIVE IMMUNE RESPONSES Ou, B.S.^; Saouaf, O.M.^; Baillet, J.; Appel, E.A.* Advanced Drug Delivery Reviews (2022) PDF
INJECTABLE POLYMER-NANOPARTICLE HYDROGEL FOR THE SUSTAINED INTRAVITREAL DELIVERY OF BIMATOPROST Meany, E.L.^; Andaya, R.^; Tang, S.; Kasse, C.M.; Fuji, R.N.; Grosskopf, A.K.; d’Aquino, A.I.; Bartoe, J.T.; Ybarra, R.; Shelton, A.; Pederson, Z.;
STABLE HIGH-CONCENTRATION MONOCLONAL ANTIBODY FORMULATIONS ENABLED BY AN AMPHIPHILIC COPOLYMER EXCIPIENT Klich, J.H.^; Kasse, C.M.^; Mann, J.L.; Huang, Y.; d’Aquino, A.I.; Grosskopf, A.K.; Baillet, J.; Fuller, G.G.; Appel, E.A.* Advanced Thera
FORMULATION EXCIPIENTS AND THEIR ROLE IN INSULIN STABILITY AND ASSOCIATION STATE IN FORMULATION Maikawa, C.L.; Nguyen, L.T.; Mann, J.L.; Appel, E.A.* Pharmaceutical Research (2022) PDF
MULTIMERIZATION OF EBOLA GPMUCIN ON PROTEIN NANOPARTICLE VACCINES HAS MINIMAL EFFECT ON ELICITATION OF NEUTRALIZING ANTIBODIES Powell, A.E.; Xu, D.; Roth, G.A.; Zhang, K.; Chiu, W.; Appel, E.A.; Kim, P.S.* Frontiers in Immunology (2022) PDF
PNP HYDROGEL PREVENTS SYMBLEPHARA FORMATION IN MICE AFTER OCULAR ALKALI INJURY Swarup, A.; Grosskopf, A.K.; Stapleton, L.M.; Subramanium, V.R.; Li, B.; Weissman, I.L.; Appel, E.A.; Wu, A.Y.* Translational Vision Science & Technology (2022
THE LIVING INTERFACE BETWEEN SYNTHETIC BIOLOGY AND BIOMATERIAL DESIGN Liu, A.P.*; Appel, E.A.; Ashby, P.D.; Baker, B.M.; Franco, E.; Gu, L.; Haynes, K.; Joshi, N.S.; Kloxin, A.M.; Kouwer, P.H.J.; Mittal, J.; Morsut, L.; Noireaux, V.; Parekh, S.